Codeine :: essays research papers

Codeine Codeine is readily absorbed from the gastrointestinal tract. It is speedily distributed from the intravascular spaces to the various body tissues, with preferential up cook by parenchymatous organs such as the liver, spleen and kidney. Codeine crosses the blood-brain barrier, and is found in fetal tissue and pap milk. The plasma concentration does non correlate with brain concentration or relief of pain however, codeine is not bound to plasma proteins and does not compose in body tissues. Treatment A single or sixfold overdose with acetaminophen and codeine is a emfly lethal poly dose overdose, and consultation with a regional poison control center is recommended. Signs and SymptomsCodeine Toxicity from codeine poisoning includes the opioid ternary of pinpoint pupils, depression of respiration, and loss of consciousness. Convulsions may occur. WHY is this drug positivist?Codeine is used, usually in combination with other medications, to reducecoughing that does not produce sputum or mucus. It is also used for reliefof bonkers to moderate pain. When used for pain, codeine is usually used withaspirin and sometimes caffeine.WHEN should it be used?Codeine is usually interpreted every four to six hours as needed. Follow thedirections on your prescription label carefully, and ask your pharmacistor doctor to explain any part that you do not understand.HOW should it be used?Codeine is available, alone or with other medications, in tablets,capsules, and liquid to be taken by mouth. Your prescription label tellsyou how much to take at apiece dose. The liquid should be shaken well beforeeach use to mix the medicine evenly. Ask your pharmacist for a especiallymarked measuring spoon to be sure of an accurate dose. Do not take more ofthis drug than irrefutable by your doctor. dangerous side effects can occur,especially in children who take as well much. Adults giving this medication toa child should be careful to slacken off the correct dose and not to give it moreoften than prescribed by the doctor. For a cough, patients older than 12 age should not take more than 120 mg of codeine a day. Children six to12 years old should not take more than 60 mg a day. A doctor should decidehow much codeine can be taken by a child two to five years old. This drugshould not be given to children younger than two years.Abuse and dependance Codeine can produce drug dependence of the morphine type and, therefore, has the potential for being abused. Psychological dependence, physical dependence, and tolerance may develop upon ingeminate administration and it should be prescribed and administered with the same degree of caution distinguish to the use of other oral narcotic medications.